Regular price $30 /month, billed quarterly
Discover Metformin, a powerful medication known for its remarkable longevity-enhancing properties. By improving insulin sensitivity, lowering blood sugar, and reducing inflammation, Metformin supports healthy aging and vitality. Studies suggest Metformin may increase lifespan, improve cognitive function, and delay age-related diseases. 
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Metformin, a well-known medication primarily prescribed for managing type 2 diabetes, has gained attention in the field of longevity due to its potential health benefits that go beyond blood sugar control. Some of the ways metformin may contribute to longevity include:

  1. Improving insulin sensitivity: Metformin helps cells respond more effectively to insulin, which can lead to better regulation of blood sugar levels and may promote overall metabolic health.
  2. Reducing inflammation: Chronic inflammation is linked to various age-related diseases and conditions. Metformin has been shown to reduce inflammation, potentially contributing to improved health and longevity.
  3. Activating AMPK: Metformin activates AMP-activated protein kinase (AMPK), an enzyme involved in cellular energy regulation. AMPK activation has been associated with increased longevity, partly due to improved metabolic function and cellular maintenance processes.
  4. Inhibiting mTOR: Metformin may inhibit the mammalian target of rapamycin (mTOR) pathway, which is involved in cell growth and proliferation. Inhibition of mTOR has been linked to increased lifespan in various organisms.
  5. Enhancing autophagy: Metformin may promote autophagy, a cellular process that clears out damaged components and recycles them for energy or building new cellular structures. Autophagy plays a crucial role in maintaining cellular health and is associated with increased longevity.

Some common side effects may include:

  1. Gastrointestinal issues: Nausea, vomiting, diarrhea, gas, bloating, or stomach pain are common gastrointestinal side effects. These issues often occur when starting metformin and may diminish as the body adjusts to the medication.
  2. Loss of appetite: Metformin may cause a reduced appetite in some individuals, which can lead to weight loss.
  3. Metallic taste: A metallic taste in the mouth is a possible side effect experienced by some people taking metformin.
  4. Headache: Some users may experience headaches while taking metformin.
  5. Weakness or fatigue: Metformin may cause feelings of weakness or fatigue in some individuals.
  6. Vitamin B12 deficiency: Long-term use of metformin can be associated with reduced vitamin B12 absorption, potentially leading to a deficiency.

Remember that while these side effects are common, they may not affect everyone taking metformin.

Metformin is not FDA-approved specifically for anti-aging purposes. However, some research suggests that it may have potential benefits in promoting longevity and delaying age-related diseases.


It's essential to consider some key safety information when taking metformin or any other medication. Here are some important points to keep in mind:

  1. Consult your healthcare provider: Always talk to your doctor before starting metformin or any new medication. They will consider your medical history, current medications, and any underlying health conditions to determine if metformin is appropriate for you.
  2. Kidney function: Metformin is primarily cleared from the body by the kidneys. If you have impaired kidney function, your doctor may need to adjust your dosage or consider alternative medications.
  3. Liver function: Individuals with liver disease should use caution when taking metformin, as it may increase the risk of lactic acidosis.
  4. Alcohol consumption: Avoid excessive alcohol intake while taking metformin, as it may increase the risk of lactic acidosis and can also worsen blood sugar control.
  5. Other medications: Inform your healthcare provider about all medications, supplements, and over-the-counter products you are taking, as they may interact with metformin.
  6. Pregnancy and breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. They will help you determine the best course of action for managing your blood sugar levels during this time.
  7. Follow dosage instructions: Take metformin as prescribed by your healthcare provider and follow their instructions regarding dosage adjustments, if necessary.
  8. Monitor blood sugar levels: Regularly monitor your blood sugar levels as directed by your healthcare provider to ensure optimal blood sugar control.
  9. Hypoglycemia risk: Metformin alone typically does not cause hypoglycemia (low blood sugar). However, if you are taking other medications for diabetes or have specific risk factors, be aware of the symptoms of low blood sugar and take appropriate action if needed.
  10. Report side effects: Inform your healthcare provider if you experience any concerning side effects or if your symptoms worsen.

Always follow your healthcare provider's recommendations and discuss any questions or concerns with them. They can provide personalized advice based on your specific situation.

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Potential Benefits

Enhanced insulin sensitivity

Promotes better blood sugar regulation and metabolic health.

Reduced inflammation

Contributes to improved health and reduced age-related disease risk.


Activates longevity pathways.

Cardiovascular health

May reduce heart disease risk and improve blood lipid profiles.

How does Metformin work

AMPK activation

Supports metabolism and cellular maintenance.

mTOR inhibition

Reduces cell growth, linked to increased lifespan.

Enhanced autophagy

Improves cellular health through damage clearance.

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From our customers

I experienced minor gastrointestinal side effects during the first few weeks of taking metformin. However, these symptoms subsided as my body adjusted to the medication. I feel great being on it after however.

Clearwater, FL

Since taking metformin, I've noticed significant improvements in my overall energy levels and mental clarity. I feel more alert throughout the day and find it easier to focus on tasks at hand. In addition, my blood work results have shown a reduction in inflammation markers, which I attribute to metformin's anti-inflammatory properties.

Los Angeles, CA

I appreciate is that metformin has helped me maintain a healthier weight. It has subtly curbed my appetite, making it easier to adhere to a balanced diet and avoid overeating. As a result, I've shed a few pounds and feel more confident in my physical health.

Austin, TX

I started using metformin for longevity purposes about six months ago, and I must say, I'm genuinely impressed with the results. I did thorough research and consulted my healthcare provider before starting, and I'm glad I made the decision to incorporate it into my health regimen.

New York, NY

I highly recommend giving metformin a try for those interested in supporting their longevity and overall health. Metformin has made a significant difference in my life, and I believe it could do the same for others!

Portland, OR